Eleanor Roosevelt Institute for Cancer Research
National Research Service Award Trainee
Eleanor Roosevelt Institute for Cancer Research, Denver, CO
National Jewish Hospital, Denver, CO
Molecular, Cellular, and Developmental Biology, University of Colorado, Boulder, CO
Eleanor Roosevelt Institute for Cancer Research, Denver, Co
Department of Molecular, Cellular, and Developmental Biology, University of Colorado, Boulder, CO
Ph.D. (Major: Anatomy, Minor: Microbiology)
Baylor University, Baylor College of Dentistry Division, Baylor University Medical Center
Professor of Anatomy & Cell Biology, Oklahoma State University College of Osteopathic Medicine (OSU-COM), Tulsa, OK
Graduate Faculty, Full Member, Oklahoma State University (OSU), Stillwater, OK
Current Services & Contributions for OSU-CHS
- OSU Faculty Council Representative for OSU-CHS – 2010-2013
- OSU Research Committee – 2010-2013
- OSU-CHS Curriculum Committee and Chair – 2010-2013
- OSU-CHS Faculty Senate Member – 2010-2013
- Oklahoma Microscopy Society Secretary/Treasurer – 2010-2013
- Member, American Association of Anatomists
- Oklahoma Microscopy Society, Secretary/Treasurer
- Microscopy Society of America
Honors & Awards
- Outstanding Professor Award, OSU-COM Class of 1998, 1994
- Provost/Dean Excellence in Teaching Award, 1998
- Regents Distinguished Teaching Award, 2008
- Regents Distinguished Teaching Award, 2013
- Outstanding Educator Award, 2013
The Role of Apoptosis in Bone Healing, Orthopaedic Trauma Association, $29,800, Investigator associated with project.
The Cytoskeleton of Intact and Cultured Synovial Membrane Cells from Patients with Rheumatoid Arthritis, Continuance Grant from American Osteopathic Association, $16,700.
The Cytoskeleton of Intact and Cultured Synovial Membrane Cells From Patients with Rheumatoid Arthritis, American Osteopathic Association, $13,500.
Representative Publications & Presentations
P.C. de Souza, F. Lupu, B. Meek, H. Chen, Y. Dong, D. Saunders, A. Orock, E. Hodges, S. Colijn, N. Mamedova, and R. Towner. (2015). 0KN-007 Decreases VEGFR-2 Levels in a Preclinical GL261 Mouse Glioma Model. Am J Nucl Med Mol Imaging, 5(4): 363-378.
Meek, W.D. and Puck, T.T., (1979). Role of the Microfibrillar System in Knob Action of Transformed Cells. J. Supramolec. Struc. 12: 335-354.
Meek, W.D., Porter, K.R. and Puck, T.T., (1980). The Ultrastructure of Process Formation Following Treatment with dbcAMP of a Chinese Hamster Ovary X Chinese Hamster Brain Cell Hybrid. Exp. Cell Res. 126: 359-374.
Puck, T.T., Erikson, R.L., Meek, W.D., and Nielson, S.E., (1981). Reverse Transformation of Vole Cells Transformed by Avian Sarcoma Virus Containing the src Gene. J. Cell Physiol. 107: 399-412.
Meek, W.D. and Henderson, D.A., (1994). Characterization of Keratin Densities in Mitotic WISH Cells. Cell Motility and Cytoskel. 28(2): 165-178.
Kolomytkin, O.V., Marino, A.A., Sadasivan, K.K., Meek, W.D., Wolf, R.E., Hall, V., McCarthy, K.J., and Albright, J.A., (2000). Gap Junctions in Human Synovial Cells and Tissue. J. Cellular Phys., 184: 110-117.
Meek, B., Rose, S., and Sands, S., (2000). Unique Cellular Features in a Testicular Plasmacytoma Case. Ultrastruc. Path., 24: 197-201.
Beju, D., Meek, W.D., Kramer, J.C. (2004). The Ultrastructure of the Nasal Polyps in Patients with and without Cystic Fibrosis. J. Submicro. Cytol. Path., 36 (2).
Wilson, N.F., Iyer, J.K., Buchheim, J.A., and Meek, W. 2008. Regulation of Flagellar Length in Chlamydomonas, Seminars in Cell Develop. Biol., 19:494-501
Sivadas, P., Dienes, J.M, Maurice, M.S., Meek, W.D., & Yang, P. (2012). RIIA and Dpy-30 Domains Dock Discrete Effectors to Two Amphipathic Helices in a Flagellar AKAP. J. Cell Biol. 199(4):639-651.
- Clinically Based Histology - MSI
- Clinical Gross Anatomy and Developmental Anatomy - MSI
- Advanced Histology - Graduate
- Medical Embryology - Graduate
My research interest is in the area of the cytoskeleton and its relationship to developmental and cellular functions. Current projects include the arrangement of vimentin intermediate filament network in epithelial cells, fine structural studies of flagellar length control and flagellar movement, and morphological assessment of a skin explant model in metastasis and dermal interaction.
I joined the faculty of the OSU College of Osteopathic Medicine anatomy department following postdoctoral fellowships at the Eleanor Roosevelt Institute for Cancer Research in Denver, Colorado, and the Molecular, Cellular, and Developmental Biology Department at the University of Colorado in Boulder, Colorado. With this background I was interested in the mechanisms of cell biology and the microscopic anatomy of the cell and its application to the cancer cell and genetic diseases.
I was trained in the area of electron microscopy and cell culture and thus worked extensively in these two fields to investigate the structure of the cell during the "early" days of scanning electron microscopy and high voltage electron microscopy. I feel privileged to have worked as the advisee of two pioneers in the areas of cell culture and electron microscopy, Ted Puck and Keith Porter.
At the time of my postdoctoral study, the structural nature of the cell was beginning to unfold with the advancement of viewing techniques in the areas of immunology and microscopy. These applications were also being applied to learning more about the metastatic properties of cancer cells. My training was firmly grounded in gross anatomy and the anatomy discipline in general, as I assisted with teaching during my graduate studies at the Baylor University Medical Center in Dallas.
- Road Bicycling
- Ballroom Dancing
- Butterfly and Beetle Collecting
- Basset Hound Watching
- Study of the Oklahoma & North Texas Panhandle