Education
1998
Ph.D. (Nutrition)
Texas Tech University
1994
M.S. (Zoology)
Oklahoma State University
1990
B.S. (Biomedical Sciences)
Oklahoma State University
Postdoctoral Research Experience
2002-2004
NRSA (NIAAA/NIH) Postdoctoral Fellow,
Texas Tech University HSC (Pharmacology & Neuroscience).
1998-2002
Postdoctoral Research Associate,
Texas Tech University HSC (Pharmacology)
Funding
2002-2004
NRSA (NIAAA/NIH, F32 AA013221), Principal Investigator, Ethanol and NOS2 Gene Expression in Human Astrocytes; 2.5 yr.
R21 (NIAAA/NIH, AA014955; Revised application under review), Principal Investigator, Ethanol Effects on Human Astroglial Chemokine Expression
Selected Publications
Inhibition of selenite-induced cytotoxicity and apoptosis in human colonic carcinoma cells (HT29) by copper. R.L. Davis, J.E. Spallholz and B.C. Pence, Nutrition and Cancer, 32(3):181-189; 1998.
In vitro vascular smooth muscle cell models: role in the study of diabetic complications and atherogenic diseases. R.L. Davis and T.E. Tenner, Jr. Current Opinion in Clinical Experimental Research, 2:225-250; 2000.
Effect of selenium supplementation on cytotoxic activity of the human NK cell line (NK3.3). R.L. Davis, C.A. Phillips, J.E. Spallholz, Nutritional Immunology, 5:99-113; 2001.
Differential indicators of diabetes-induced oxidative stress in New Zealand White rabbits: Role of dietary vitamin E supplementation. R. L. Davis, C. L. Lavine, M. A. Arredondo, P. McMahon and T. E. Tenner Jr. Experimental Diabetes Research 3:1-7; 2002.
Ethanol-induced modulation of NOS-2 expression in human astrocytoma (A172) cells. R.L. Davis, J. Dertein and P.J. Syapin. Alcoholism Clinical and Experimental Research 26:1404-1411; 2002.
Identification of cis-regulatory regions necessary for robust NOS2 promoter activity in glial cells: Indirect role for NF- k B. A.C. Sanchez, R.L. Davis,P.J. Syapin. Journal of Neurochemistry 86: 1379-1390 ; 2003.
Chronic ethanol inhibits CXC chemokine ligand 10 production in human A172 astroglia and astroglial-mediated leukocyte chemotaxis. R.L. Davis , P.J. Syapin. Neuroscience Letters 362: 220-225; 2004.
Acute ethanol exposure modulates expression of inducible nitric-oxide synthase in human astroglia: Evidence for a transcriptional mechanism. R.L. Davis, P.J. Syapin. Alcohol 32(3):195-202; 2004.
Ethanol increases nuclear factor- k B p65 activity in human astroglia. R.L. Davis, P.J. Syapin. Neuroscience Letters (in press); 2004.
Research Interests
Neuroinflammation: modulation of proinflammatory pathways in human glial cells by various drugs and dietary compounds.
Non-academic Interests
Soccer and Golf
