Education
1989
Ph.D. (Physiology)
Medical College of Georgia
Augusta, GA
1984
M.S. (Life Sciences)
University of Tennessee
Knoxville, TN
1976
B.S. (Engineering)
United States Military Academy
West Point, NY
Postdoctoral Training
1989-1992
Postdoctoral Fellowship
Nephrology Research and Training Center
University of Alabama at Birmingham
Professional Experience
1997-Present
Associate Professor of Physiology,
Oklahoma State University College of Osteopathic Medicine (OSU-COM),
Tulsa, OK
1992-1997
Assistant Professor of Physiology,
OSU-COM
Service & Contributions
- Faculty Senate President,
OSU-COM, 2000-2001
- Chair, Institutional Animal Care and Use Committee,
OSU-COM, 1994-2000
- Member, Academic Standards Committee,
OSU-COM, 1999-Present
- Chair, Biomedical Sciences Graduate Committee,
OSU-COM (Organizing the graduate program), 1997-2000
- President,
Oklahoma Society of Physiologists, 1998
- Secretary/Treasurer,
Oklahoma Society of Physiologists, 1998-Present
Professional Societies
- American Physiological Society
- Society for Experimental Biology and Medicine
- Oklahoma Academy of Sciences
- Oklahoma Society of Physiologists
Extramural Funding
1995-1999
Effect of nerves on kidney function, National Science Foundation, $150,000
1992-1994
Effect of lumen pH on sodium and potassium transport in the collecting duct. OCAST, $53,208
Representative Publications & Presentations
Refereed Jounal Articles
Schafer, J.A., L. Chen, C.T. Hawk, L. Kudo, and A.J. Rouch. Synergism of vasopressin and aldosterone actions Na+ transport in the rat cortical collecting duct. Aldosterone: Fundamental Aspects. 215: 219-228, 1991.
Schafer, J.A., L. Chen, and A.J. Rouch. The role of vasopressin in the regulation of Na+ and K+ transport in the cortical collecting duct. Vasopressin. 208: 493-501, 1991. (Proc. Third Internat. Congress on Vasopressin, Montpellier, France).
Rouch, A.J., S.L. Troutman, L. Chen, and J.A. Schafer. Na+ transport in rat CCD: Effects of bradykinin, ANP, hydrochlorothiazide, and clonidine. Am. J. Physiol. 260 (Renal Fluid Electrolyte Physiol. 29): F86-F95 1991.
Rouch, A.J., G.M. Whitford, and H.T. Campbell. Fluoride flux in the rabbit CCD: A pH-dependent event. Kidney International. 41: 342-349, 1992.
Hawk, C.T., L.H. Kudo, A.J. Rouch, and J.A. Schafer. Inhibition by epinephrine of AVP-and cAMP-stimulated Na+ and water transport in Dahl rat CCD. Am. J. Physiol. 256 (Renal Fluid Electrolyte Physiol. 34): F449-F460, 1993.
Rouch, A.J., L. Chen, L.H. Kudo, P.D. Bell, B.C. Fowler, B.D. Corbitt, and J.A. Schafer. Intracellular Ca2+ and PKC activation do not inhibit Na+ and water transport in rat CCD. Am. J. Physiol. 265 (Renal Fluid Electrolyte Physiol. 34): F569-F577, 1993.
Rouch, A.J. and L.H. Kudo. a2-Adrenergic-mediated inhibition of water and urea permeability in the rat IMCD. Am. J. Physiol. 271 (Renal Fluid and Electrolyte Physiol. 40): F150-F157,1996.
Rouch, A.J., L.H. Kudo, and C.A. Hébert. Dexmedetomidine inhibits osmotic water permeability in the rat cortical collecting duct. J. Pharmacol. Exp. Ther. 281: 62-69, 1997.
Rouch, A.J. and L.H. Kudo. Indomethacin and staurosporine reverse a2 inhibition of water transport in rat IMCD. Kidney International. 52: 1351-1358, 1997.
Rouch, A.J., C.A. Hébert, and L.H. Kudo. Inhibition of water permeability in the rat collecting duct: effect of imidazoline and alpha-2 compounds. Proc. Soc. Exp. Biol. Med. 221:136-146, 1999.
Rouch, A.J. and L.H. Kudo. Role of PGE2 in a2-induced inhibition of AVP- and cAMP-stimulated H2O, Na+ and urea transport in the rat IMCD. Am J Physiol. Renal. 279: F294-F301, 2000.
Book Chapters
Rouch, A.J. Hormonal Effects on Urinary Acidification. In Handbook of Endocrinology, 2nd ed., ed. by G.H. Gass and H.M. Kaplan, pp. 67-79, CRC Press, 1996.
Rouch, A.J. Mecanismos de Acidificação Urinária. In Princípios de Nefrologia e Distúrbios Hidroelectrolíticos, 3rd ed., ed. by M. C. Riella, pp. 39-43, 1996.
Recreational Interests
Instructional Activities
- Medical Physiology (Renal and GI Physiology) - MS I
- Epithelial Transport and Electrophysiology - Graduate
Research Interests
Epithelial Transport
Research involves receptor-mediated transport mechanisms of salt and water in the kidney. The research is related to the renal regulation of blood pressure. Goals are to identify specific membrane receptors, intracellular mediators, and signal-transduction mechanisms that regulate sodium and water movement in the kidney.
Biographical Information
I joined the university in June 1992 as an Assistant Professor in Physiology. As a faculty member I am responsible for teaching, research, and service. Teaching physiology to medical students requires not only presenting the fundamentals of the physiological systems (neural, cardiovascular, renal, gastrointestinal, respiratory, and endocrine) but also enabling the students to integrate the systems in such a way that develops a full understanding of how the human body functions. Research requires an active participation in the discovery of new knowledge and sharing that knowledge with colleagues, students, and the community. Service requires participating on university committees and taking an active role in developing appropriate policies for the college.
