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Mary Bea Drummond | 918-594-8223

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Sean Kennedy | 918-594-8360

Grant from Cancer Sucks Supports OSU-CHS research

TULSA, Okla. – A $10,000 grant from Cancer Sucks, Inc., to the Oklahoma State University Center for Health Sciences has helped to purchase an Accuri C6 Flow Cytometer System for cancer research.
 
Rashmi Kaul, Ph.D., associate professor of immunology and researcher, said, “We sincerely thank Cancer Sucks for its generous support of our cancer research, especially in these tough economic times. The Cancer Sucks’ contribution has enabled us to secure matching funds for the $25,200 purchase of this instrument.”

Dr. Kaul said the cytometer will help with cancer research as well and clinical research, especially in conducting studies to understand how Hepatitis C in the liver leads to development of cancer. She explained that the full-feature flow cytometer is an automated instrument that quantifies properties of single cells, one cell at a time and is widely used in the characterization of various human cancers. It can measure cell size, cell granularity, total cellular DNA, a particular gene expression, amounts of specific cell surface receptors, amounts of intracellular proteins, or signaling events in living cells. The information can be used to determine how well a cancer may respond to a particular treatment.

“The information about DNA is important, because the total DNA per cell in biopsy specimens from cancers is monitored for clinical cancer diagnosis and prognosis,” Dr. Kaul said.  “The cytometer also is used to quantify different immune cell types such as CD4+ vs. CD8+ T lymphocytes in blood to determine when an HIV infection has resulted in AIDS and the degree to which anti-HIV drugs are working.”

 “We will be able to use this instrument for our on-going cancer research as well as infectious disease research in our laboratory, mainly to investigate features of different human cell populations including normal, infected or transformed cancer cells. In addition, we will also be processing cells from biological fluids from different patients enrolled in clinical studies at various clinics undergoing various treatment conditions,” she said.

Dr. Kaul said that both biomedical and clinical science investigators at OSU-CHS will be able to use this equipment for their research investigations and for educating students, including those in a proposed project for summer biomedical research training program at OSU-CHS for area disadvantaged middle and high school students.

Matching funds have been secured from the Oklahoma National Science Foundation EPSCoR Research Infrastructure Improvement (RII) Award and the NIH IDeA Network for Biomedical Research Excellence (INBRE) Award.  Installation of the new instrument is planned for later this year.

Cancer Sucks, Inc. has supported cancer research at OSU since 2006. More information about the organization is available at www.cancersucks.com. The organization’s purpose is to provide a forum for those who have lost loved ones to cancer while aggressively raising money to find a cure.