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Medical Physiology - Evidence-Based Medicine Tutorial
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What is EBM?

Patient Care Model
Life-long Learning
Why is EBM Important?
Available Evidence?
EBM Issues

The Well-built Question

The EBM Process
Anatomy of a Question

Finding Evidence

Selecting a Resource
Searching the Resource
Reviewing Search Results
Returning to the Patient

Evaluating Evidence

Evaluating the Validity
Validity Questions


Knowledge Test

Multiple Sclerosis
Case #2
Case #3
Case #4




If you are a student in PE-8618/BIOM-5616 Class, please enter your name below and submit for credit. Please submit your name once for each time you take the tutorial.



Welcome. This tutorial is intended as a basic introduction to the principles of Evidence-Based Medicine for medical students in the Neurophysiology section of the Medical Physiology course (PE-8616). Upon completion of this self-paced tutorial, you will be able to:

  • Define Evidence-Based Medicine (EBM)

  • Identify the parts of a well-built clinical question

  • Find the best evidence using first choice point-of-care databases

  • Identify key issues that help determine the validity of the results of a study

This tutorial is not designed to teach you how to search for evidence in the large scale, primary research literature index databases like MEDLINE, PubMed, and EMBASE. Instead, this tutorial teaches how to find evidence in the new generation, point-of-care knowledge databases like: DynaMed, UpToDate, and FIRSTConsult. These knowledge databases provide evidence-based answers to specific clinical questions quickly enough for real-time clinical scenarios.

To start the tutorial go to the first section, What is EBM: Patient Care Model.


This tutorial teaches you basic principles and concepts of EBM. For more information about EBM resources and research, see Evidence-Based Medicine.



© 2008 Oklahoma State University Center for Health Sciences Medical Library

Select content and organization used with permission of Duke University Medical Center Library and the Health Sciences Library, UNC-Chapel Hill.


How to use this Tutorial

The units in this tutorial are always listed at the top of the screen. You may leave a unit at any time, start over at any time, or even skip a section.Each unit of this tutorial is a web page. The topics covered in a unit appear at the top of each unit page. Click on a topic to go directly to that section. This tutorial includes five major units. We recommend that you go through them in sequence. They will give you an overview of the Evidence-Based Medicine process as well as give you an opportunity to practice with new cases. The five units are:

  • What is Evidence-Based Medicine?
    provides definitions and explains the steps in the EBM process.

  • The Well-Built Clinical Question introduces you to a patient, illustrates the anatomy of a good clinical question, and defines the types of questions and studies.

  • Finding the Evidence
    finds the best evidence using first choice point-of-care databases.

  • Evaluating the Evidence
    identifies criteria for determining the validity of a study.

  • Testing your Knowledge
    gives you an opportunity to practice the EBM process with several new cases.
In addition to the above units, this tutorial includes the following sections:
  • References and Glossary
    points you to additional sites for continued study of the EBM process, and defines some of the terms used in EBM. All cited references are included in this unit.
  • Feedback
    gives you the opportunity to provide feedback about this tutorial. We ask that you take the time to give us your thoughts and suggestions for improvement. All comments will be greatly appreciated.

Within this tutorial, you have several opportunities to follow links to other web sites. The external sites open in a new window. Close the second window to return to this tutorial.

We hope this tutorial will be easy to use as well as give you a foundation for the process of Evidence-Based Medicine (EBM).

Allow approximately 2 hours to complete the tutorial and 1 practice case.