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Center for Health Sciences
Medical Physiology - Evidence-Based Medicine
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What is EBM?

Patient Care Model
Life-long Learning
Why is EBM Important?
Available Evidence?
EBM Issues

The Well-built Question

The EBM Process
Anatomy of a Question

Finding Evidence

Selecting a Resource
Searching the Resource
Reviewing Search Results
Returning to the Patient

Evaluating Evidence

Evaluating the Validity
Validity Questions


Knowledge Test

Multiple Sclerosis
Case #2
Case #3
Case #4




Reviewing the Search Results

The evaluation

4. Appraise that evidence for its validity (closeness to the truth) and applicability (usefulness in clinical practice to a particular patient)

In our search for "stroke" in DynaMed in the previous unit we found a conclusion about oral nutritional supplements based on a (level 1 [likely reliable] evidence) study published in Lancet. Since the validity of this study has been pre-assessed by the editors of DynaMed, this saves us a lot of time. Having received a level 1 assessment this study meets our criteria for validity.

We can now consider the applicability question. If DynaMed's summary does not give enough data to answer this question, then clicking on the EBSCOhost Full Text link after the Lancet source statement will display the full text article which contains all essential data of the study.



We now go to Returning to the Patient